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Article

A common motif within the negative regulatory regions of multiple factors inhibits their transcriptional synergy.

Molecular and cellular biology - 1 Aug 2000

Iñiguez-Lluhí J A, Pearce D

Abstract excerpt

DNA regulatory elements frequently harbor multiple recognition sites for several transcriptional activators. The response mounted from such compound response elements is often more pronounced than the simple sum of effects observed at single binding sites. The determinants of such transcriptional synergy and its control, however, are poorly understood. Through a genetic approach, we have uncovered a novel protein...

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Identifiers

PMID: 10913186
DOI: 10.1128/MCB.20.16.6040-6050.2000
PMCID: PMC86080

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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