Article
Effects of deletion or stringent repression of the H3L envelope gene on vaccinia virus replication.
Journal of virology - 1 Aug 2000
da Fonseca F G, Wolffe E J, Weisberg A, Moss B
Abstract excerpt
The C-terminal membrane anchor protein encoded by the H3L open reading frame of vaccinia virus is located on the surfaces of intracellular mature virions. To investigate the role of the H3L protein, we constructed deletion (vH3Delta) and inducible (vH3i) null mutants. The H3L protein was not detected in lysates of cells infected with vH3Delta or vH3i in the absence of inducer. Under these conditions, plaques were...
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