Article
Envelope formation is blocked by mutation of a sequence related to the HKD phospholipid metabolism motif in the vaccinia virus F13L protein.
Journal of virology - 1 Feb 1999
Roper R L, Moss B
Abstract excerpt
The outer envelope of the extracellular form of vaccinia virus is derived from Golgi membranes that have been modified by the insertion of specific viral proteins, of which the major component is the 37-kDa, palmitylated, nonglycosylated product of the F13L gene. The F13L protein contains a varia...
Topics
- Acylation
- Amino Acid Sequence
- Animals
- Binding Sites
- Cell Fusion
- Cell Line
- Centrifugation, Density Gradient
- Cesium
- Chlorides
- Chlorocebus aethiops
- Gene Expression
- HeLa Cells
- Humans
- Membrane Proteins
- Molecular Sequence Data
- Mutagenesis
- Octoxynol
- Phenotype