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Article

Envelope formation is blocked by mutation of a sequence related to the HKD phospholipid metabolism motif in the vaccinia virus F13L protein.

Journal of virology - 1 Feb 1999

Roper R L, Moss B

Abstract excerpt

The outer envelope of the extracellular form of vaccinia virus is derived from Golgi membranes that have been modified by the insertion of specific viral proteins, of which the major component is the 37-kDa, palmitylated, nonglycosylated product of the F13L gene. The F13L protein contains a variant of the HKD (His-Lys-Asp) motif, which is conserved in numerous enzymes of phospholipid metabolism. Vaccinia virus...

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Identifiers

PMID: 9882312
DOI: 10.1128/JVI.73.2.1108-1117.1999
PMCID: PMC103931

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Envelope formation is blocked by mutation of a sequence related to the HKD phospholipid metabolism motif in the vaccinia virus F13L protein.PMID 9882312Read ↗

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