Article
Genomic structure, chromosomal localization, and expression pattern of the human LIM-homeobox3 (LHX 3) gene.
Biochemical and biophysical research communications - 21 Jul 2000
Schmitt S, Biason-Lauber A, Betts D, Schoenle E J
Abstract excerpt
Lhx3 is a LIM-homeobox protein essential for pituitary development in mice. The human homologue gene spans 7.2 kb and contains 7 exons, including two alternatively spliced first exons. This structure encodes two distinct protein isoforms, LHX3a and LHX3b, that differ exclusively in their amino-terminus. The LHX3 gene was localized at 9q34.2-34.3. The predicted protein sequence is highly homologous to other known...
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