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Article

Cell-specific actions of a human LHX3 gene enhancer during pituitary and spinal cord development.

Molecular endocrinology (Baltimore, Md.) - 1 Dec 2013

Park Soyoung, Mullen Rachel D, Rhodes Simon J

Abstract excerpt

The LIM class of homeodomain protein 3 (LHX3) transcription factor is essential for pituitary gland and nervous system development in mammals. In humans, mutations in the LHX3 gene underlie complex pediatric syndromes featuring deficits in anterior pituitary hormones and defects in the nervous system. The mechanisms that control temporal and spatial expression of the LHX3 gene are poorly understood. The proximal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24100213
DOI: 10.1210/me.2013-1161
PMCID: PMC3857196

Genes

LHX3
GATA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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