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Article

Expression and function of the LIM homeobox containing genes Lhx3 and Lhx4 in the mouse placenta.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 May 2008

Tian Geng, Singh Umashankar, Yu Yang, Ellsworth Buffy S, Hemberger Myriam, Geyer Rudolf, Stewart M David, Behringer Richard R, Fundele Reinald

Abstract excerpt

The LIM homeobox containing genes of the LIM-3 group, Lhx3 and Lhx4, are critical for normal development. Both genes are involved in the formation of the pituitary and the motoneuron system and loss of either gene causes perinatal lethality. Previous studies had shown that Lhx3 is overexpressed in hyperplastic placentas of mouse interspecies hybrids. To determine the role of LHX3 in the mouse placenta, we...

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Source

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Identifiers

PMID: 18425848
DOI: 10.1002/dvdy.21546
PMCID: PMC3632286

Genes

LHX3
LHX4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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