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Article

Rab1 recruitment of p115 into a cis-SNARE complex: programming budding COPII vesicles for fusion.

Science (New York, N.Y.) - 21 Jul 2000

Allan B B, Moyer B D, Balch W E

Abstract excerpt

The guanosine triphosphatase Rab1 regulates the transport of newly synthesized proteins from the endoplasmic reticulum to the Golgi apparatus through interaction with effector molecules, but the molecular mechanisms by which this occurs are unknown. Here, the tethering factor p115 was shown to be a Rab1 effector that binds directly to activated Rab1. Rab1 recruited p115 to coat protein complex II (COPII) vesicles...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10903204
DOI: 10.1126/science.289.5478.444

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Rab1 recruitment of p115 into a cis-SNARE complex: programming budding COPII vesicles for fusion.PMID 10903204Read ↗

The interaction of two tethering factors, p115 and COG complex, is required for Golgi integrity.Semantic proximity Read ↗

The membrane transport factor TAP/p115 cycles between the Golgi and earlier secretory compartments and contains distinct domains required for its localization and function.Semantic proximity Read ↗

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