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The Golgi vesicle tether p115/USO1 can bind directly to the ER exit site organiser Sec16A

2025-10-16

Abstract excerpt

<h4>ABSTRACT</h4> Newly-made secretory and membrane proteins exit the endoplasmic reticulum (ER) in COPII vesicles that form at specialised ER exit sites. These exit sites are typically near to the early Golgi compartments that receive these vesicles. A key player in the delivery of vesicles to the early Golgi is p115 (USO1), a homodimer with a folded head domain and a coiled-coil tail that is anchored to Golgi m...

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Identifiers and source

Literature Corpus work
2988adc4-8acb-59d7-bd58-b69625ceeb96
DOI
10.1101/2025.10.16.682774
Open publication

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