Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between -308G/A TNFA Polymorphism and Susceptibility to Type 2 Diabetes Mellitus: A Systematic Review.

Journal of diabetes research - 1 Jan 2016

Luna Geisa Izetti, da Silva Izabel Cristina Rodrigues, Sanchez Mauro Niskier

Abstract excerpt

Diabetes mellitus (DM) is considered to be a worldwide epidemic disease and its type 2 form comprises more than 95% of all cases. Tumor necrosis factor-alpha (TNF-α) is a proinflammatory cytokine. Its dysregulation has been implicated in a variety of human diseases, including type 2 diabetes mellitus (T2DM). The control of expression of this cytokine is associated with insulin resistance and has a strong genetic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diabetes Mellitus, Type 2
Share to TNF gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Polymorphism, Single Nucleotide

Share to Tumor Necrosis Factor-alpha

Source

Open in PubMed Open full text

Identifiers

PMID: 27822481
DOI: 10.1155/2016/6309484
PMCID: PMC5086378

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between -308G/A TNFA Polymorphism and Susceptibility to Type 2 Diabetes Mellitus: A Systematic Review.PMID 27822481Read ↗

The TNF-alpha -308G/A polymorphism is associated with type 2 diabetes mellitus: an updated meta-analysis.Semantic proximity Read ↗

Meta-analysis of TNF 308 G/A polymorphism and type 2 diabetes mellitus.Semantic proximity Read ↗

The association of TNF-α -308G/A and -238G/A polymorphisms with type 2 diabetes mellitus: a meta-analysis.Semantic proximity Read ↗

The role of TNF-α G-308A promoter polymorphism in glycemic control in Type 2 diabetes patients.Semantic proximity Read ↗

Investigations of associations between TNF-α promoter polymorphisms and genetic susceptibility to type 2 diabetes mellitus: A cross-sectional study in Chinese Han population.Semantic proximity Read ↗

A meta-analysis of the association between TNF-α -308G>A polymorphism and type 2 diabetes mellitus in Han Chinese population.Semantic proximity Read ↗

TNF-alpha polymorphisms and type 2 diabetes mellitus in Taiwanese patients.Semantic proximity Read ↗

Associations between TNF gene polymorphisms (-308 A/G, -238 A/G, -1031 C/T and -857 T/C) and genetic susceptibility to T1D: a meta-analysis.Semantic proximity Read ↗

Genetic variants of tumor necrosis factor-α and its levels: A correlation with dyslipidemia and type 2 diabetes susceptibility.Semantic proximity Read ↗

TNF-α (−308) Gene Polymorphism and Type 2 Diabetes Mellitus in Ethiopian Diabetes PatientsSemantic proximity Read ↗

Tumor necrosis factor-α (TNF-α) -863C/A promoter polymorphism is associated with type 2 diabetes in Tunisian population.Semantic proximity Read ↗

Association of -308 TNF-alpha promoter polymorphism with type 1 diabetes in North Indians.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.