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Article

Fates of human B-cell precursors

1 Jul 2000

Abstract excerpt

Development of mammalian B-lineage cells is characterized by progression through a series of checkpoints defined primarily by rearrangement and expression of immunoglobulin genes. Progression through these checkpoints is also influenced by stromal cells in the microenvironment of the primary tissues wherein B-cell development occurs, ie, fetal liver and bone marrow and adult bone marrow. This review focuses on...

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PMID: 10891425
DOI: 10.1182/blood.v96.1.9

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