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Article

IL13 variants are associated with total serum IgE and early sensitization to food allergens in children with atopic dermatitis.

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology - 1 Sept 2009

Zitnik Simona Eva, Rüschendorf Franz, Müller Sebastian, Sengler Claudia, Lee Young-Ae, Griffioen Rupino W, Meglio Paolo, Wahn Ulrich, Witt Heiko, Nickel Renate

Abstract excerpt

Increased total and specific serum immunoglobulin E (IgE) levels are common characteristics of atopic diseases and their basal production is proposed to be under strong genetic control. Interleukin 13 (IL13) variants have been consistently associated with total serum IgE levels in white populatio...

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Identifiers

PMID: 19220774
DOI: 10.1111/j.1399-3038.2008.00815.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19220774-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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IL13 variants are associated with total serum IgE and early sensitization to food allergens in children with atopic dermatitis.PMID 19220774Read ↗

An IL13 coding region variant is associated with a high total serum IgE level and atopic dermatitis in the German multicenter atopy study (MAS-90).Semantic proximity Read ↗

Analysis of IL-13 gene polymorphisms in pediatric patients with food allergy.Semantic proximity Read ↗

Genetic variation at the Th2 immune gene IL13 is associated with IgE-mediated paediatric food allergy.Semantic proximity Read ↗

A cluster of seven tightly linked polymorphisms in the IL-13 gene is associated with total serum IgE levels in three populations of white children.Semantic proximity Read ↗

Atopic dermatitis phenotype with early onset and high serum IL-13 is linked to the new development of bronchial hyperresponsiveness in school children.Semantic proximity Read ↗

Interleukin-13 promoter gene polymorphism -1112 C/T is associated with atopic dermatitis in Polish patients.Semantic proximity Read ↗

Epigenetics and development of food allergy (FA) in early childhood.Semantic proximity Read ↗

Impact of interleukin 13 (IL13) genetic polymorphism Arg130Gln on total serum immunoglobulin (IgE) levels and interferon (IFN)-γ gene expression.Semantic proximity Read ↗

An allergy-associated polymorphism in a novel regulatory element enhances IL13 expression.Semantic proximity Read ↗

IL13 gene polymorphism association with cord serum immunoglobulin E.Semantic proximity Read ↗

A polymorphism in the coding region of interleukin-13 gene is associated with atopy but not asthma in Chinese children.Semantic proximity Read ↗

IL-13 R130Q, a common variant associated with allergy and asthma, enhances effector mechanisms essential for human allergic inflammation.Semantic proximity Read ↗

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