Article
Interleukin-13 promoter gene polymorphism -1112 C/T is associated with atopic dermatitis in Polish patients.
Acta dermatovenerologica Croatica : ADC - 1 Jan 2012
Gleń Jolanta, Trzeciak Magdalena, Sobjanek Michał, Bandurski Tomasz, Wilkowska Aleksandra, Nedoszytko Bogusław, Roszkiewicz Jadwiga, Sokołowska-Wojdyło Małgorzata
Abstract excerpt
Interleukin 13 (IL-13) is one of the major cytokines involved in the IgE synthesis in patients with atopic dermatitis (AD). IL-13 gene has been mapped on chromosome 5q31-33 region associated with atopic conditions, where several polymorphisms are described. The aims of the study were to establish the frequency of the IL-13 gene polymorphism and its relation to serum IgE and IL-13 levels and SCORAD. In 180 AD...
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