Article
Polymorphisms in the IL4, IL4RA, and FCERIB genes and asthma severity.
The Journal of allergy and clinical immunology - 1 Jul 2000
Sandford A J, Chagani T, Zhu S, Weir T D, Bai T R, Spinelli J J, Fitzgerald J M, Behbehani N A, Tan W C, Paré P D
Abstract excerpt
BACKGROUND: Genetic polymorphisms have been associated with asthma and asthma severity. OBJECTIVE: We sought to determine whether 3 polymorphisms were associated with severe asthma indicated either by the occurrence of a fatal (or near-fatal) asthma attack or by severe airflow obstruction. METHODS: We obtained DNA and clinical data from asthmatic subjects who either died or nearly died during an asthma attack and...
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