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Article

Asthma severity, nature or nurture: genetic determinants.

Current opinion in pediatrics - 1 Jun 2019

Raby Benjamin A

Abstract excerpt

PURPOSE OF REVIEW: This article reviews the progress in the search for the genetic determinants of severe asthma. RECENT FINDINGS: Twin studies estimate that approximately 25% of the phenotypic variability in asthma severity is determined by genetic factors, with the remainder determined by nongenetic factors including environmental and psychosocial factors, behavioral traits, and comorbidities. Most genetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 31090575
DOI: 10.1097/MOP.0000000000000758

Genes

MUC5AC
GATA3
GSDMB
IL13
ORMDL3
RAD50

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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