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Article

Association of IL4RA polymorphism in predicting susceptibility toward chronic obstructive pulmonary disease.

Pharmacogenomics - 1 Jul 2023

Pandit Depanshi, Sharma Parul, Yadav Harsh, Garg Kranti, Chopra Vishal, Sharma Siddharth

Abstract excerpt

Background: The cytokine IL-4 plays vital role in the intercellular signalling network during immune responses to allergen exposure. Methods: This cross-sectional study involved 202 chronic obstructive pulmonary disease (COPD) patients and 203 healthy individuals. The genotyping of IL4RAQ576R gene polymorphism was determined using PCR restriction fragment length polymorphism analysis. Results: Significant...

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PMID: 37551548
DOI: 10.2217/pgs-2023-0010

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