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Article

P53 alterations have no prognostic or predictive significance in Dukes' C rectal carcinomas.

International journal of oncology - 1 Dec 1999

Elsaleh H, Soontrapornchai P, Grieu F, Joseph D, Iacopetta B

Abstract excerpt

We investigated the prognostic significance of p53 alterations in a consecutive series of 122 Dukes' C rectal carcinomas with a median patient follow-up period of 56 months. One third of patients were treated with post-operative adjuvant chemotherapy. Overexpression of p53 protein was observed in 42% (50/118) of cases using immunohistochemical analysis and mutation of the p53 gene in 38% (47/122) using single...

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Share to Antimetabolites, Antineoplastic
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Polymorphism, Single-Stranded Conformational

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Source

Identifiers

PMID: 10568834
DOI: 10.3892/ijo.15.6.1239

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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