Article
Regulation of cyclooxygenase-2 and periostin by Wnt-3 in mouse mammary epithelial cells.
The Journal of biological chemistry - 13 Oct 2000
Haertel-Wiesmann M, Liang Y, Fantl W J, Williams L T
Abstract excerpt
Wnt family members are critical in developmental processes and have been shown to promote carcinogenesis when ectopically expressed in the mouse mammary gland. The gene expression pattern mediated by Wnt is pivotal for these diverse responses. The Wnt pathway has been conserved among different species. Genetic studies have shown that Wnt effects are mediated, at least in part, by beta-catenin, which regulates...
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