Specific modulation of ectodermal cell fates in Xenopus embryos by glycogen synthase kinase.

doi:10.1242/dev.121.12.3979

Back to search

Article

Specific modulation of ectodermal cell fates in Xenopus embryos by glycogen synthase kinase.

Development (Cambridge, England) - 1 Dec 1995

Itoh K, Tang T L, Neel B G, Sokol S Y

Abstract excerpt

Shaggy is a downstream component of the wingless and Notch signaling pathways which operate during Drosophila development. To address the role of glycogen synthase kinase 3 beta (GSK3 beta), a mammalian homologue of Shaggy, in vertebrate embryogenesis, it was overexpressed in Xenopus embryos. Mic...

Topics

Animals
Base Sequence
Calcium-Calmodulin-Dependent Protein Kinases
Cell Lineage
DNA Primers
Ectoderm
Eye
Gene Expression
Glycogen Synthase Kinase 3
Glycogen Synthase Kinases
Molecular Sequence Data
Phenotype
Rats
Signal Transduction
Xenopus

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.