Article
Plasmodium falciparum–Infected Erythrocytes: Agglutination by Diverse Kenyan Plasma Is Associated with Severe Disease and Young Host Age
1 Jul 2000
Abstract excerpt
The variant surface antigens (VSAs) of Plasmodium falciparum-infected red blood cells are potentially important targets of naturally acquired immunity to malaria. Natural infections induce agglutinating antibodies specific to the VSA variants expressed by the infecting parasites. Previously, when different parasite isolates were tested against a panel of heterologous plasma from Kenyan children, the proportion of...
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