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Article

Reduced virulence of Candida albicans mutants lacking the GNA1 gene encoding glucosamine-6-phosphate acetyltransferase.

Microbiology (Reading, England) - 1 Jul 2000

Mio Toshiyuki, Kokado Michiko, Arisawa Mikio, Yamada-Okabe Hisafumi

Abstract excerpt

The yeast GNA1 gene encodes glucosamine-6-phosphate acetyltransferase which catalyses the reaction of glucosamine 6-phosphate with acetyl-CoA to form N-acetylglucosamine 6-phosphate, a fundamental precursor in UDP-N-acetylglucosamine biosynthesis. Candida albicans mutants lacking GNA1 were viable in the presence of N-acetylglucosamine. To confirm the physiological importance of C. albicans GNA1, the virulence of...

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PMID: 10878139
DOI: 10.1099/00221287-146-7-1753

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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