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Article

Molecular Characterization of the N-Acetylglucosamine Catabolic Genes in Candida africana, a Natural N-Acetylglucosamine Kinase (HXK1) Mutant.

PloS one - 1 Jan 2016

Felice Maria Rosa, Gulati Megha, Giuffrè Letterio, Giosa Domenico, Di Bella Luca Marco, Criseo Giuseppe, Nobile Clarissa J, Romeo Orazio, Scordino Fabio

Abstract excerpt

BACKGROUND: In this study we report the genetic characterization, including expression analysis, of the genes involved in the uptake (NGT1) and catabolism (HXK1/NAG5, DAC1/NAG2, NAG1) of the aminosugar N-acetylglucosamine (GlcNAc) in Candida africana, a pathogenic biovariant of Candida albicans that is naturally unable to assimilate the GlcNAc. RESULTS: DNA sequence analysis of these genes revealed a number of...

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PMID: 26808192
DOI: 10.1371/journal.pone.0147902
PMCID: PMC4726466

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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