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Article

Unanticipated heterogeneity in growth rate and virulence among Candida albicans AAF1 null mutants.

Infection and immunity - 1 Jul 1999

Rieg G, Fu Y, Ibrahim A S, Zhou X, Filler S G, Edwards J E

Abstract excerpt

The disruption of a specific gene in Candida albicans is commonly used to determine the function of the gene product. We disrupted AAF1, a gene of C. albicans that causes Saccharomyces cerevisiae to flocculate and adhere to endothelial cells. We then characterized multiple heterozygous and homozygous mutants. These null mutants adhered to endothelial cells to the same extent as did the parent organism. However,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 10377090
DOI: 10.1128/IAI.67.7.3193-3198.1999
PMCID: PMC116495

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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