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Article

Low virulence of a morphological Candida albicans mutant.

FEMS microbiology letters - 15 Jul 1999

Diez-Orejas R, Molero G, Ríos-Serrano I, Vázquez A, Gil C, Nombela C, Sánchez-Pérez M

Abstract excerpt

The virulence of Candida albicans 92', a morphological mutant unable to filament, was assayed in an experimental model of systemic candidiasis in three strains of mice with different susceptibilities to the infection. The mortality parameters studied pointed to the low virulence of this mutant strain. Study of the fungal load of C. albicans 92' in kidneys and brain revealed the presence of low numbers of CFUs and...

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PMID: 10427713
DOI: 10.1111/j.1574-6968.1999.tb13677.x

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