Article
Correlation between virulence of Candida albicans mutants in mice and Galleria mellonella larvae.
FEMS immunology and medical microbiology - 11 Oct 2002
Brennan Marc, Thomas David Y, Whiteway Malcolm, Kavanagh Kevin
Abstract excerpt
Candida albicans is a dimorphic human pathogen in which the yeast to hyphal switch may be an important factor in virulence in mammals. This pathogen has recently been shown to also kill insects such as the Greater Wax Moth Galleria mellonella when injected into the haemocoel of the insect larvae. We have investigated the effect of previously characterised C. albicans mutations that influence the yeast to hyphal...
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