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Article

Using sex-averaged genetic maps in multipoint linkage analysis when identity-by-descent status is incompletely known.

Genetic epidemiology - 1 Jul 2006

Fingerlin Tasha E, Abecasis Gonçalo R, Boehnke Michael

Abstract excerpt

The ratio of male and female genetic map distances varies dramatically across the human genome. Despite these sex differences in genetic map distances, most multipoint linkage analyses use sex-averaged genetic maps. We investigated the impact of using a sex-averaged genetic map instead of sex-specific maps for multipoint linkage analysis of affected sibling pairs when identity-by-descent states are incompletely...

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PMID: 16685713
DOI: 10.1002/gepi.20151

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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