Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic diversity in the matrix metalloproteinase family. Effects on function and disease progression.

Annals of the New York Academy of Sciences - 1 May 2000

Henney A M, Ye S, Zhang B, Jormsjö S, Whatling C, Eriksson P, Hamsten A

Abstract excerpt

Atherosclerosis is an example of a complex trait, where the course of the disease is influenced by a combination of common variation in a constellation of genes and the effect of a wide range of environmental variables. Thus, the underlying disease mechanisms will be modulated by genetic diversity and the effect this diversity has on an individual's response to environmental challenges such as smoking, diet, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arteriosclerosis
Share to Chromosome Mapping

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human

Share to Disease Progression

Share to Genetic Variation

Share to Matrix Metalloproteinases

Share to Tissue Inhibitor of Metalloproteinases

Source

Identifiers

PMID: 10865823
DOI: 10.1111/j.1749-6632.2000.tb06298.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic diversity in the matrix metalloproteinase family. Effects on function and disease progression.PMID 10865823Read ↗

Molecular Mechanisms Regulating Matrix MetalloproteinasesSemantic proximity Read ↗

Classification, regulation of activity, and genetic polymorphism of matrix metalloproteinases in health and diseaseSemantic proximity Read ↗

Polymorphism in matrix metalloproteinase gene promoters: implication in regulation of gene expression and susceptibility of various diseasesSemantic proximity Read ↗

MMP-1 polymorphism and its relationship to pathological processes.Semantic proximity Read ↗

Genetic variation at the matrix metalloproteinase-9 locus on chromosome 20q12.2-13.1.Semantic proximity Read ↗

Molecular characterization of matrix metalloproteinase gene family across primatesSemantic proximity Read ↗

Unraveling metalloproteinase function in skeletal biology and disease using genetically altered miceSemantic proximity Read ↗

Single nucleotide polymorphism-specific regulation of matrix metalloproteinase-9 by multiple miRNAs targeting the coding exon.Semantic proximity Read ↗

Matrix metalloproteinases and atherogenesis in dependence of age.Semantic proximity Read ↗

Single nucleotide polymorphisms of tissue inhibitor of metalloproteinase genes in familial moyamoya disease.Semantic proximity Read ↗

Genome-wide association scan identifies variants near Matrix Metalloproteinase (MMP) genes on chromosome 11q21-22 strongly associated with serum MMP-1 levels.Semantic proximity Read ↗

Matrix metalloproteinases in atherothrombosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.