Article
Genetic variation at the matrix metalloproteinase-9 locus on chromosome 20q12.2-13.1.
Human genetics - 1 Nov 1999
Zhang B, Henney A, Eriksson P, Hamsten A, Watkins H, Ye S
Abstract excerpt
Allelic association methods are better suited than linkage analysis for mapping of susceptibility genes that confer modest increases in risk in complex diseases. In both family- and population-based association studies, it is very useful to have prior knowledge of all sequence variants and the degree of linkage disequilibrium in a candidate gene region. In this study, we scanned sequence variants in a 2.2-kb...
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