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Molecular Mechanisms Regulating Matrix Metalloproteinases

1 Apr 2012

Abstract excerpt

The family of matrix metalloproteinases (MMPs) comprises 24 multidomain enzymes with a zinc-dependent activity. Their structural diversity over the archetypal domain organization confers variable biological function to these molecules ranging from cellular homeostasis and control of tissue turnover to implication in multiple pathological conditions such as inflammation, arthritis, cardiovascular disease and...

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PMID: 22519442
DOI: 10.2174/1568026611208011095

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