Article

Classification, regulation of activity, and genetic polymorphism of matrix metalloproteinases in health and disease

2017-01-01

Abstract excerpt

Matrix metalloproteinases (MMPs) are a family of zinc-containing endopeptidases that catalyze the degradation reactions of the extracellular matrix components. In humans, 23 enzymes of this family are known, which are subdivided into 6 groups based on their structure and substrate types: collagenases, gelatinases, stromelysins, matrilizines, MMP membrane type and other MMPs. MMP functions are diverse, and an imbal...

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Literature Corpus work: 27a7f21e-bad9-5775-bb52-03c26fd4ce6c
DOI: 10.18786/2072-0505-2017-45-4-266-279

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