Article
MMP-1 polymorphism and its relationship to pathological processes.
Journal of biosciences - 1 Jun 2009
Arakaki P A, Marques M R, Santos M C L G
Abstract excerpt
Matrix metalloproteinases (MMPs) are a family of zinc (Zn)-dependent endopeptidases that are collectively capable of cleaving virtually all extracellular matrix (ECM) substrates and play an important role in diverse physiological and pathological processes. The activity of MMPs is regulated at multiple levels. The transcriptional regulation of MMP appears to represent the key step in MMP regulation. There are...
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