Article
Evidence from mutational specificity studies that yeast DNA polymerases delta and epsilon replicate different DNA strands at an intracellular replication fork.
Journal of molecular biology - 2 Jun 2000
Karthikeyan R, Vonarx E J, Straffon A F, Simon M, Faye G, Kunz B A
Abstract excerpt
Although polymerases delta and epsilon are required for DNA replication in eukaryotic cells, whether each polymerase functions on a separate template strand remains an open question. To begin examining the relative intracellular roles of the two polymerases, we used a plasmid-borne yeast tRNA gen...
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