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Article

Genetic factors affecting the impact of DNA polymerase delta proofreading activity on mutation avoidance in yeast.

Genetics - 1 May 1999

Tran H T, Degtyareva N P, Gordenin D A, Resnick M A

Abstract excerpt

Base selectivity, proofreading, and postreplication mismatch repair are important for replication fidelity. Because proofreading plays an important role in error correction, we have investigated factors that influence its impact in the yeast Saccharomyces cerevisiae. We have utilized a sensitive mutation detection system based on homonucleotide runs of 4 to 14 bases to examine the impact of DNA polymerase delta...

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Identifiers

PMID: 10224242
DOI: 10.1093/genetics/152.1.47
PMCID: PMC1460598

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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