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Article

Actuation of CRP activating region 3 by acetylation modulates <i>V. cholerae</i> sugar utilization and virulence

2026-01-27

Abstract excerpt

The cyclic AMP receptor protein or CRP is a global regulator of bacterial metabolism that activates transcription of genes required for utilization of alternative carbon sources in response to the second messenger cAMP, which is synthesized in the setting of glucose scarcity. CRP activates transcription through contact with RNA polymerase at three sites termed activating regions (ARs) 1-3. AR3 was previously repor...

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Literature Corpus work
7cc1ffba-ae9b-572b-b08c-f8873f06a86e
DOI
10.64898/2026.01.27.701997
Open publication

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Actuation of CRP activating region 3 by acetylation modulates <i>V. cholerae</i> sugar utilization and virulenceDOI 10.64898/2026.01.27.701997
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