Article
Genetic locus for streptolysin S production by group A streptococcus.
Infection and immunity - 1 Jul 2000
Nizet V, Beall B, Bast D J, Datta V, Kilburn L, Low D E, De Azavedo J C
Abstract excerpt
Group A streptococcus (GAS) is an important human pathogen that causes pharyngitis and invasive infections, including necrotizing fasciitis. Streptolysin S (SLS) is the cytolytic factor that creates the zone of beta-hemolysis surrounding GAS colonies grown on blood agar. We recently reported the discovery of a potential genetic determinant involved in SLS production, sagA, encoding a small peptide of 53 amino...
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