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Article

Reduced virulence of group A streptococcal Tn916 mutants that do not produce streptolysin S.

Infection and immunity - 1 Apr 1998

Betschel S D, Borgia S M, Barg N L, Low D E, De Azavedo J C

Abstract excerpt

Streptolysin S (SLS) is a potent cytolytic toxin produced by nearly all group A streptococci (GAS). SLS-deficient Tn916 insertional mutants were generated from two clinical isolates of GAS, MGAS166s and T18Ps (M serotypes 1 and 18, respectively), by transposon mutagenesis using Tn916 donor strain...

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Identifiers

PMID: 9529097
DOI: 10.1128/IAI.66.4.1671-1679.1998
PMCID: PMC108104

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-9529097-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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