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Article

Genetic basis for the beta-haemolytic/cytolytic activity of group B Streptococcus.

Molecular microbiology - 1 Jan 2001

Pritzlaff C A, Chang J C, Kuo S P, Tamura G S, Rubens C E, Nizet V

Abstract excerpt

Group B streptococci (GBS) express a beta-haemolysin/cytolysin that contributes to disease pathogenesis. We report an independent discovery and extension of a genetic locus encoding the GBS beta-haemolysin/cytolysin activity. A plasmid library of GBS chromosomal DNA was cloned into Escherichia coli, and a transformant was identified as beta-haemolytic on blood agar. The purified plasmid contained a 4046 bp insert...

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Source

Identifiers

PMID: 11136446
DOI: 10.1046/j.1365-2958.2001.02211.x

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Source receipt: pubmed, retrieved 7 Sept 2026.

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