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Article

Streptococcal beta-hemolysins: genetics and role in disease pathogenesis.

Trends in microbiology - 1 Dec 2002

Nizet Victor

Abstract excerpt

A zone of beta-hemolysis surrounding colonies on blood-agar media is a hallmark phenotypic feature of the pathogens group A Streptococcus (GAS) and group B Streptococcus (GBS). In each case, lysis of red blood cells reflects the action of a potent protein exotoxin. Although these toxins have been the subjects of numerous investigations over the years, their purification and molecular identification have proven...

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PMID: 12564994
DOI: 10.1016/s0966-842x(02)02473-3

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