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Article

Regulation of the β-hemolysin gene cluster of Streptococcus anginosus by CcpA.

Scientific reports - 13 Jun 2018

Bauer Richard, Mauerer Stefanie, Spellerberg Barbara

Abstract excerpt

Streptococcus anginosus is increasingly recognized as an opportunistic pathogen. However, our knowledge about virulence determinants in this species is scarce. One exception is the streptolysin-S (SLS) homologue responsible for the β-hemolytic phenotype of the S. anginosus type strain. In S. anginosus the expression of the hemolysin is reduced in the presence of high glucose concentrations. To investigate the...

Topics

Bacterial Proteins
Base Sequence
Binding Sites
Computer Simulation
Gene Expression Regulation, Bacterial
Glucose
Hemolysin Proteins
Multigene Family
Mutation
Promoter Regions, Genetic
Streptococcal Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Streptococcus anginosus

Streptolysins

Virulence

Source

Open in PubMed Open full text

Identifiers

PMID: 29899560
DOI: 10.1038/s41598-018-27334-z
PMCID: PMC5998137

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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