Article
New gene cluster for lantibiotic streptin possibly involved in streptolysin S formation.
Journal of biochemistry - 1 May 2001
Karaya K, Shimizu T, Taketo A
Abstract excerpt
Streptolysin S (SLS) is a serum-extractable and oxygen-stable hemolysin produced by Group A Streptococcus. A SLS-deficient mutant in which transposon Tn 916 was inserted in a locus distinct from the sag gene cluster [Nizet et al. (2000) Infect. Immun. 68, 4245-4254] was obtained by filter mating of the transposon-harbouring Enterococcus faecalis strain and Streptococcus pyogenes BL(T). This mutant, N22, had...
Topics
- Anti-Bacterial Agents
- Bacterial Proteins
- Bacteriocins
- Base Sequence
- Cloning, Molecular
- DNA Transposable Elements
- Hemolysin Proteins
- Multigene Family
- Mutation
- Open Reading Frames
- Peptides
- Streptococcus pyogenes
- Streptolysins
