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Article

Functional Analysis of the Quorum-Sensing Streptococcal Invasion Locus (sil)

5 Nov 2009

Abstract excerpt

Group A streptococcus (GAS) causes a wide variety of human diseases, and at the same time, GAS can also circulate without producing symptoms, similar to its close commensal relative, group G streptococcus (GGS). We previously identified, by transposon-tagged mutagenesis, the streptococcal invasion locus (sil). sil is a quorum-sensing regulated locus which is activated by the autoinducer peptide SilCR through the...

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PMID: 19893632
DOI: 10.1371/journal.ppat.1000651

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