Article
Snail is an immediate early target gene of parathyroid hormone related peptide signaling in parietal endoderm formation.
The International journal of developmental biology - 1 Apr 2000
Veltmaat J M, Orelio C C, Ward-Van Oostwaard D, Van Rooijen M A, Mummery C L, Defize L H
Abstract excerpt
In mouse development, parietal endoderm (PE) is formed from both primitive endoderm (PrE) and visceral endoderm (VE). This process can be mimicked in vitro by using F9 embryonal carcinoma cells (EC) cells, differentiated to PrE or VE cells, and treating these with Parathyroid Hormone related Peptide (PTHrP). By means of differential display RT-PCR, we identified Snail (Sna) as a gene upregulated during the...
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