Article

LIN28-mediated gene regulatory loops synchronize developmental transitions throughout organogenesis

2025-01-22

Abstract excerpt

<h4>ABSTRACT</h4> Precise control of the intervals between self-renewal, proliferation, and differentiation of stem/progenitor cells are coordinated by developmental regulators, comprised of both microRNAs (miRNAs) and proteins, termed heterochronic genes. These heterochronic factors make up a unique subset of evolutionarily conserved genes that regulate the developmental rate and timing of metazoans from worms t...

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Literature Corpus work: 336d23b5-8ec9-54f1-a3ed-432938706ad4
DOI: 10.1101/2025.01.22.634324

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