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Article

The mouse snail gene encodes a key regulator of the epithelial-mesenchymal transition.

Molecular and cellular biology - 1 Dec 2001

Carver E A, Jiang R, Lan Y, Oram K F, Gridley T

Abstract excerpt

Snail family genes encode DNA binding zinc finger proteins that act as transcriptional repressors. Mouse embryos deficient for the Snail (Sna) gene exhibit defects in the formation of the mesoderm germ layer. In Sna(-/-) mutant embryos, a mesoderm layer forms and mesodermal marker genes are induced but the mutant mesoderm is morphologically abnormal. Lacunae form within the mesoderm layer of the mutant embryos,...

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Identifiers

PMID: 11689706
DOI: 10.1128/MCB.21.23.8184-8188.2001
PMCID: PMC99982

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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