Precise gene localization by phenotypic assay of radiation hybrid cells.

doi:10.1073/pnas.130200097

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Precise gene localization by phenotypic assay of radiation hybrid cells.

Proceedings of the National Academy of Sciences of the United States of America - 20 Jun 2000

Rasko J E, Battini J L, Kruglyak L, Cox D R, Miller A D

Abstract excerpt

A high resolution map of the human genome previously has been constructed by using the G3 panel of human/hamster radiation hybrid cell lines and >15,000 unique human genetic markers. By determining whether human DNA sequences are present or absent in each of the hybrids, localization of single genes may routinely be achieved at approximately 250-kb resolution. In this paper we have tested whether similarly...

Topics

Animals
Cell Line
Chromosome Mapping
Cricetinae
Genome, Human
Humans
Hybrid Cells
Phenotype
X-Rays

Source

Open in PubMed Open full text

Identifiers

PMID: 10852967
DOI: 10.1073/pnas.130200097
PMCID: PMC16555

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics