High-frequency transformation of human repair-deficient cell lines by an Epstein-Barr virus-based cDNA expression vector.

doi:10.1016/0378-1119(91)90328-9

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Article

High-frequency transformation of human repair-deficient cell lines by an Epstein-Barr virus-based cDNA expression vector.

Gene - 15 Nov 1991

Peterson C, Legerski R

Abstract excerpt

We constructed a human cDNA expression vector by combining an episomal Epstein-Barr virus (EBV) vector with the expression cassette from the transient-expression vector, pCDM8. This new vector, designated pEBS7, exhibited high-level expression of reporter genes in normal and repair-deficient xero...

Topics

Antigens, Viral
Base Sequence
Cell Line
DNA Repair
Epstein-Barr Virus Nuclear Antigens
Gene Expression
Gene Library
Genetic Vectors
Herpesvirus 4, Human
Humans
Molecular Sequence Data
Phenotype
Plasmids
Transfection
Xeroderma Pigmentosum

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