Article
Efficient identification and regional positioning of YAC and cosmid clones to human chromosome 21 by radiation fusion hybrids.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jun 1994
Kumlien J, Labella T, Zehetner G, Vatcheva R, Nizetic D, Lehrach H
Abstract excerpt
The use of integrated mapping strategies involving bacterial, yeast, and rodent cells as hosts simplifies the construction of maps, which combine long-range order, high resolution, and easy access to the cloned DNA. Radiation-fusion hybrids offer a specially powerful long-range mapping system for human chromosomes. We describe here techniques for establishing a radiation-fusion hybrid map of Chromosome (Chr) 21q...
Topics
- Animals
- Chromosome Mapping
- Chromosomes, Artificial, Yeast
- Chromosomes, Human, Pair 21
- Cricetinae
- Escherichia coli
- Genetic Markers
- Genetic Techniques
- Genetic Vectors
- Genotype