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Article

Tagging of genes involved in multidrug resistance in Aspergillus nidulans.

Molecular & general genetics : MGG - 1 May 2000

de Souza C C, Goldman M H, Goldman G H

Abstract excerpt

We have used a plasmid containing the Neurospora crassa pyr4 gene to transform an Aspergillus nidulans pyrG89 mutant strain in the presence of Bam-HI, and isolated multidrug-sensitive mutants among the transformants. Using this approach, we hoped to identify genes whose products are important for drug resistance by analyzing gene disruptions that alter the drug sensitivity of the cell. About 1300 transformants...

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Identifiers

PMID: 10852493
DOI: 10.1007/s004380051219

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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