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Article

New regulators of drug sensitivity in the family of yeast zinc cluster proteins.

The Journal of biological chemistry - 14 Jun 2002

Akache Bassel, Turcotte Bernard

Abstract excerpt

The Gal4p family of yeast zinc cluster proteins comprises over 50 members that are putative transcriptional regulators. For example, Pdr1p and Pdr3p activate multidrug resistance genes by binding to pleiotropic drug response elements (PDREs) found in promoters of target genes such as PDR5, encoding a drug efflux pump involved in resistance to cycloheximide. However, the role of many zinc cluster proteins is...

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Identifiers

PMID: 11943786
DOI: 10.1074/jbc.M202566200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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