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Article

The unusual inheritance of multidrug-resistance factors in Saccharomyces.

Current genetics - 1 Aug 1996

Shallom J M, Golin J

Abstract excerpt

The yeast PDR5 locus encodes a 160-kDa member of the ABC family of transport proteins. Strains bearing a deletion of this locus are drug hypersensitive. Resistant revertants arise when cells are plated on cycloheximide medium. About one-third of these are cross resistant to other agents, includin...

Topics

ATP-Binding Cassette Transporters
Antifungal Agents
Crosses, Genetic
Cycloheximide
Drug Resistance, Multiple
Fluconazole
Fungal Proteins
Genes, Fungal
Genetic Linkage
Genotype
Membrane Proteins
Microbial Sensitivity Tests

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Oligomycins

Recombination, Genetic

Saccharomyces cerevisiae

Saccharomyces cerevisiae Proteins

Sulfonylurea Compounds

Source

Identifiers

PMID: 8753649
DOI: 10.1007/s002940050123

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8753649-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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