Article
Drug-induced phenotypes provide a tool for the functional analysis of yeast genes.
Yeast (Chichester, England) - 1 Jul 1998
Launhardt H, Hinnen A, Munder T
Abstract excerpt
The post-genome sequencing era of Saccharomyces cerevisiae is defined by the analysis of newly discovered open reading frames of unknown function. In this report, we describe a genetic method for the rapid identification and characterisation of genes involved in a given phenotype. This approach i...
Topics
- Antifungal Agents
- Benomyl
- Cytochrome P-450 Enzyme System
- Drug Resistance
- Electron Transport Complex IV
- Ergosterol
- Gene Dosage
- Genes, Fungal
- Ketoconazole
- Membrane Proteins
- Miconazole
- Molecular Biology
- Mutagenesis
- Open Reading Frames
- Oxidoreductases
- Phenotype
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins